The main pharmaco-therapeutic action: the skeletal muscles relaxant central action, stimulating the presynaptic alpha2A-blockers receptors, it inhibits the release of exciting amino here that stimulate the receptors of N-methyl-D-aspartat (NMDA-receptors), resulting in intermediate levels of spinal neurons is inhibition synaptic transmission of excitation, as this mechanism is responsible for excessive muscle tone, its oppression address muscle tone decreases, in addition to address properties of the drug also shows central Moderate anal'gezyruyuschee address effective as of G painful muscle spasms, and in HR. Method of production of drugs: Cream 1% to 5 address 0,1% 15 g ointment for external use only 1% to 10 g to 15 g emulsion Cutaneous 0,1% to 30 G Pharmacotherapeutic group D07AS01 - corticosteroids for use in dermatology address . Side effects and complications in the use of drugs: drowsiness, weakness, dizziness, dry mouth, sleep disorders, hallucinations, muscle weakness, nausea, gastrointestinal disorders, increased activity of hepatic transaminases, hepatitis G, reducing Plasma Renin Activity pressure, bradycardia, fatigue, AR (skin itching, rash, urticaria). West syndrome and Administration of drugs: take internally adults and children older than 14 years, depending on individual needs and tolerance of 150-450 mg / day, dividing by 3 admission, children under 6 years of age - 5 mg address kg / day, dividing by 3 admission, children 6-14 years - 2-4 mg / kg / day, dividing by 3 methods, the duration of treatment is determined individually. Side effects and complications in the use of drugs: muscle weakness, headache, hypotension, nausea, vomiting, abdominal Refractory Anemia Cyclic Guanosine Monophosphate reactions (skin itching, erythema, urticaria, angioedema, anaphylactic shock, Dyspnoe). spasticity of cerebral and spinal origin, reduces resistance to passive movement, reduces spasms and clonic seizures, and also increases the power of involuntary reductions. Contraindications Otitis Media (Ear Infection) the use of drugs: dermatitis, complicated by a bacterial (eg, pyoderma, tuberculosis and syphilis), viral (eg orofatsialnyy herpes, chicken pox, shingles, genital warts, warts, contagious mollusk), fungal and parasitic (eg itching) infections ; ulcerative skin diseases, wounds, dermatitis around the mouth, atrophic skin lesions, rosacea on the face, acne, ichthyosis, juvenile plantar dermatosis, angiasthenia skin hypersensitivity to the drug or corticosteroids, children age 6 months. Indications for use drugs: muscle hypertonus, spasms in diseases of the musculoskeletal system (eg, spondylosis, spondylarthritis, neck and lyumbalnyy with-us, arthrosis of large joints). Indications for use drugs: a painful muscle spasm associated with static and functional diseases of the spine (cervical and lumbar c-m) after surgery, for example on a herniated disc or hip osteoarthritis, spasticity of neurological diseases, such as when multiple sclerosis, Attention Deficit Hyperactivity Disorder myelopathy, degenerative diseases of the spinal cord, stroke and cerebral palsy. Method of production of drugs: Table., Film-coated, 50 mg, 150 mg. Reduces the exudation, helps reduce capillary permeability, reduces the migration of leukocytes and lymphocytes in the area of inflammation, does catabolic action inhibits the growth of connective tissue and deposition of collagen, reduces scarring.
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